Description
> 100,000 Different GPCR Binding Motifs- With over 100,000 different GPCR binding motifs, unlock the discovery of antibodies to this difficult-to-target class.
GPCRS ARE HARD-TO-DRUG- 30-50% of current drug targets are GPCRs but there are only 2 FDA approved antibodies
- Current antibody drug development methods do not work
- Random mutagenesis libraries are too inefficient to explore the effective sequence space
SYNTHETIC LIBRARY ADVANTAGE- No immunization required
- Synthetic mAb libraries focus on effective sequence space
- Simultaneous screening against multiple targets